Effedt of menopause on fertility hormones and associated biochemical parameters

ABSTRACT

Serum calcium, cholesterol and fertility hormones of fifty two healthy women before and after menopause were investigated. Women who had gone through menopause had elevated levels of Leuteinizing Hormone [LH] [P< 0.0001], and Follicle Stimulating Hormone [FSH] [P< 0.0001], and lower serum Estradio [P< 0.0001]. Mean Progesterone level was 0.6 +/- 0.1 mg/ml during the follicular phase of normal menstrual cycle in premenopausal women and 0.5 +/- 0.1 mg/ml in postmenopausal women. Besides, the serum concentrations of both calcium [P< 0.0001] and cholesterol [P< 0.05] were found higher after menopause. Hence, it is concluded that the pattern of fertility hormones and associated biochemical parameters as observed in our study was identical in trends with corresponding conventional normal values