Status of haemostasis in patients with peptic ulcers having haemorrhagic complication [In Anamnesis]

ABSTRACT

Peptic ulcer is one of the common diseases in the world. Most frequent and sometimes dramatic complication of peptic ulcer is haemorrhage. According to different authors, 20-60% of the patients with peptic ulcer present with gastroduodenal haemorrhage. Pathogenesis of haemorrhage was attributed to disturbances of haemostatic system. However, the data regarding this is small and controversial, Earlier studies were mostly devoted to the study of plasma factors but recently interest has grown in the cellular mechanisms of haemostasis i,e, adhesive and aggregative properties of thrombocytes and erythrocytes. In this paper an effort is made to summarize all published data regarding haemostatic status of peptic ulcer patients with particular attention to those with a history of haemorrhage in anamnesis