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Cytotoxic cardenolides from cheiranthus cheiri L. flowers
Bulletin of Faculty of Pharmacy-Cairo University. 1998; 36 (3): 147-9
in English | IMEMR | ID: emr-47810
ABSTRACT
The ethanolic extract of the flowers of the Egyptian species of Cheiranthus cheiri L. [Cruciferae] showed significant cytotoxicity against 2 different cancer cell lines. Bioassay-guided fractionation led to the isolation of 2 cardenolides, strophanthidin 1, and helveticoside 2, where the latter demonstrated potent activity against 6 cell lines tested, especially A-549 [human lung carcinoma]. This study was the first report for the isolation of cardenolides from the flower of Cheiranthus cheiri L. and the first report for cytotoxicity of helveticoside
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Index: IMEMR (Eastern Mediterranean) Main subject: Plants / Cytotoxicity Tests, Immunologic / Cardenolides Language: English Journal: Bull. Fac. Pharm.-Cairo Univ. Year: 1998

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Index: IMEMR (Eastern Mediterranean) Main subject: Plants / Cytotoxicity Tests, Immunologic / Cardenolides Language: English Journal: Bull. Fac. Pharm.-Cairo Univ. Year: 1998