Cytotoxic cardenolides from cheiranthus cheiri L. flowers
Bulletin of Faculty of Pharmacy-Cairo University. 1998; 36 (3): 147-9
in English
| IMEMR
| ID: emr-47810
ABSTRACT
The ethanolic extract of the flowers of the Egyptian species of Cheiranthus cheiri L. [Cruciferae] showed significant cytotoxicity against 2 different cancer cell lines. Bioassay-guided fractionation led to the isolation of 2 cardenolides, strophanthidin 1, and helveticoside 2, where the latter demonstrated potent activity against 6 cell lines tested, especially A-549 [human lung carcinoma]. This study was the first report for the isolation of cardenolides from the flower of Cheiranthus cheiri L. and the first report for cytotoxicity of helveticoside
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Plants
/
Cytotoxicity Tests, Immunologic
/
Cardenolides
Language:
English
Journal:
Bull. Fac. Pharm.-Cairo Univ.
Year:
1998
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