Utilities of 4- [4'benzyl phenyl] 6-Arylpyrimidine-2-thiones for the synthesis of biologically active condensed and non-condensed heterocycles

ABSTRACT

The pyrimidine nucleus has been employed as a basis for the synthesis of chemotherapeutic agents and a large number of its derivatives have been reported to possess various biological properties such as antitumour, antimalarial, antiinflammatory, antibacterial and other pharmacological properties[1-5] Prompted by these observations pyrimidine-thione I is used now as a building block for the synthesis of new condensed and non-condensed heterocyclic compounds