Mycotoxins [aflatoxins and ochratoxins] in blood of pre-eclamptic and eclamptic egyptian patients and their relation to myocotoxins in the umbliocal cord blood and the fetal outcome umblical

ABSTRACT

This study included 172 primigravid mothers, 98 had preeclampsia, 22 had eclamptic fits, and 52 were normal pregnants. Aflatoxins were detected in 70.4% and 90.9% in maternal blood samples of preeclamptic and eclamptic patients, respectively, compared with none in the control. They were detected in 67.3%, 90.95%, and 1.9% in the fetal blood of preeclamptic, eclamptic and control groups, respectively. There was no significant difference in Aflatoxins [Afs] between maternal and fetal blood. Ochratoxin A could not be detected in maternal blood of the control group or in the fetal blood samples of all groups. Aflatoxin B1 was the most abundant aflatoxin in the maternal and fetal blood samples. Aflatoxin M1 and M2 could not be detected in the umbilical cord blood samples. There was significant high level of AfB1 in the umbilical cord blood of unhealthy babies [small for date, neonatal distress and neonatal jaundice] compared with healthy babies