Helicobacter pylori infection among diabetic patients

ABSTRACT

In this study 40 NIDDM patients [group A] and 25 IDDM patients [group B] were compared to age matched 30 non-diabetic subjects as control [group C]. All studied subjects were complaining of dyspeptic symptoms. The studied groups had their clinical background, body weight, blood sugar levels, endoscopic and histopathologic data analyzed. Helicobacter pylori was diagnosed by means of rapid urease test, histological staining for H. pylori like organism and serological assessment of anti-H. pylori IgG antibodies. Results showed statistically higher prevalence of H. pylori infection as well as chronic gastritis and reflux esophagitis among diabetic groups compared to non-diabetic dyspeptic patients. This could be related to defective gastric emptying and tendency for bacterial colonization among diabetic patients. Motility studies were warranted in such cases