Cervical ripening. A double blind controlled trial of PGE2 pessary

ABSTRACT

OBJECTIVE: To determine the efficacy of PGE2 pessary in the cervical ripening and to study its effect on other parameters of labour and delivery. DESIGN: Prospective study. SETTING: Maternity Unit II Nishtar Hospital Multan. SUBJECT A randomized double blind trail of PGE2 pessary was carried out in patients admitted for induction of labour. MEASUREMENT AND RESULT: We looked at the change in Bishop scoring, induction delivery interval, mode of delivery and fetal outcome. Fifty% of the patients who received prostin E2 pessary went into labour before planned amniotomy while only five% of the patients receiving placebo did so. No significant difference was found in mode of delivery and incidence of fetal distress between the two groups. The shortened induction delivery interval following pre treatment with PGE2 [3 mg] pessary