Myelodysplastic syndromes: a case report and treatment experience with 5-azacitidine.

ABSTRACT

Myelodysplastic syndromes [MDS] are a clonal haematological disorder of one or more cell line with resultant cytopenias. Complications encountered include infection, hemorrhage, anemia and evolution into acute leukemia. MDS are difficult to treat and except for allogenic bone marrow transplant, rest of treatment like low dose chemotherapy differentiating agents and growth factors, should be considered palliative. We are presenting our experience about a case of MDS and a newer chemotherapeutic agent, 5-azacytidine which was used in this case to treat MDS, with good results: