Failure of diclophenac sodium suppository to augment nalbuphine hydro-chloride post-operative analgesia after day care surgery

ABSTRACT

To see the efficacy of Diclofenac Sodium Suppository [DSS] in augmenting the effect of nalbuphine hydrochloride for pain. Design: A comparative study of diclofenac sodium suppository and placebo suppository. Setting: Breast clinic of Sir Ganga Ram Hospital Lahore. Subjects: 50 female patients admitted for lump breast surgery. Fifty female patients who were to undergo surgery were given diclofenac sodium suppository or placebo one hour before surgery. There was no difference in the pain score 3 to 6 hours after intramuscular injection of Nalbuphine Hydrochloride in 0.2mg/kg. Failure of diclofenac sodium suppository to augment nalbuphine. P values indicate that patients experiencing pain at various times is not significantly different in the two groups. Conclusion. Uneven absorption of diclofenac sodium suppository or rectum loaded with faeces may produce poor results: