Recent advances in pharmaceutical applications of solid phase synthesis
SPJ-Saudi Pharmaceutical Journal. 1998; 6 (1): 1-36
in English
| IMEMR
| ID: emr-49796
ABSTRACT
Merrifield in 1963 introduced his solid phase technique for synthesis of peptides. The advantage of this approach is that the growing peptide chain is firmly attached to a completely insoluble solid particle and can be washed free of reagents and by-products. It was for reason that the term solid phase peptide synthesis was introduced to describe the new method. This method lends itself to automation and provides a route to the synthesis of many of the higher molecular weight polypeptides and oligonucleotides which have not been accessible by conventional procedures
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Polymers
/
Pharmaceutical Preparations
Language:
English
Journal:
Saudi Pharm. J.
Year:
1998
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