Applicable study for using the skin as a dialytic membrane in patients with chronic renal failure

ABSTRACT

Twenty patients with chronic renal failure [CRF] were subjected to immersion up to the neck in a bathing basin containing 200 liters of dialysate fluid at 37C for one hour. Serum urea and creatinine were evaluated before and after immersion; a significant decrease in serum urea[10.47%] and an insignificant decrease in serum creatinine [5.36%] were found after immersion. This simple type of dialysis can minimize the need for regular hemodialysis. Some points should be reevaluated to magnify the value of the resultant decrease in serum urea and creatinine; the volume of the dialysate fluid, the concentration gradient between patients serum and dialysate fluid and the temperature of the dialysate fluid and duration of immersion