Synthesis of some thiazolidinone and triazole dderivatives of expected antimicrobial activity
Bulletin of Faculty of Pharmacy-Cairo University. 1999; 37 (2): 33-40
in English
| IMEMR
| ID: emr-50463
ABSTRACT
New derivatives of semicarbazide [5] and thiosemicarbazide [6] had been synthesized together with new substituted alkyl and aryl 1, 2, 4-triazoles [7] and thiazolidinone [8] obtained by cyclizing the appropriate thiosemicarbazide [6]. Screening for antibacterial and antifungal activities using preliminary scan by the agar plate inhibition zone method, followed by MIC versus ampicillin and clotrimazole revealed high activity for compounds [5-c] and [7-a]. The partition coefficient of the most and least biologically active compounds was determined and the results were reported
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Thiazoles
/
Triazoles
/
Anti-Infective Agents
Language:
English
Journal:
Bull. Fac. Pharm.-Cairo Univ.
Year:
1999
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