Clinical studies of [procopper iud] and in-vivo evaluation of levonorgestrel and copper levels in different biological fluids

ABSTRACT

The clinical studies of procopper IUDs revealed that they decreased the menstrual flow, but not to the extent of amenorrhea, no pregnancy was reported and they diminished pelvic inflammatory disease [PID]. The in vivo release study of both levonorgestrel as well as copper released from procopper IUDs in biological fluids indicated that neither levonorgestrel nor copper interfered with the release of each other, indicating that there is no interaction between them