Synthesis of some new heterocycles from poenzimidazole - 2 - Acetonitrile and their antinicrobial activity

ABSTRACT

The reaction of benzimidazole-2-acetonitrile 2 with chalcones la and b gave the corresponding benzimidazolo substituted hydropyridines 3 and 5, benzimidazolyl substituted hydropyridines 7 and 8, benzimidazolyl substituted pyrone 4, benzimidazolyl substituted coumarin 6 and benzimidazolyl substituted cyclohexanol 9 depending on the catalyst used and reaction temperature. The analytical and spectral data were recorded and the biological activity of these products against some bacteria and fungi was screened