lipid and flovonoidal constituents of Aerva javonica webb in hook. F. and their antimicrobial activity

ABSTRACT

The flavonoidal constituents isolated from ethyl acetate fraction of aqueous alcoholic extract of Aerva javanica [var. Bovi] were identified as chrysoeriol, isorhamnetin 3-0-rutinoside and kaempferol 3-0-robinoside using MP, PC, TLC, UV, 1H-NMR and MS analyses. Also, the lipid content was studied. GLC analysis of unsaponifiable fraction revealed the presence of a series of hydrocarbons ranging from C13-C30; in addition, campsterol, beta-sitosterol and the triterpenoid alpha- and beta-amyrin as well as fatty alcohol fraction ranging from C26-C36 were identified. The fatty acid fraction revealed the presence of 14 fatty acids, in which pentadecanoic acid represented the major constituent [20.39%]. The ethyl acetate extract showed a significant antimicrobial activity against G -ve bacteria, yeast and fungi; while, the isolated flavonoidal compounds, isorhamnetin 3-0-rutinoside and chrysoeriol, showed a marked activity against G -ve bacteria. On the other hand, the fatty acids mixture showed a great activity against G -ve and G +ve bacteria, while fatty alcohols showed a significant activity against G +ve bacteria