Antibacterial activity of certanin indigenous drugs and drug plants against certain bacterial species

ABSTRACT

In the present investigation, an effort has been made to enhance the therapeutic spectrum of indigenous drugs and drug plants by testing their efficacy against certain bacterial test organisms [pathogenic as well as non-pathogenic] and by comparing their strength with known antibiotics. Aqueous decocted extract of two drugs viz. Triphala churan and Chyavanprash and two drug plants viz. Adhatoda vasica and Azadirachta indica have been evaluated against Escherichia coli, Sarcina lutea, Bacillus megaterium and Bacillus [biocontrol]. Triphala churan was profoundly effective against all test organisms, but Chyavanprash was effective against Bacillus megaterium and Escherichia coli. Leaf extract of Azadirachta indica was ineffective on all the test organisms, while leaf extract of Adhatoda vasica was effective only against Bacillus [biocontrol]. There was a definite correlation between drugs concentration and their efficacy. Out of the three test antibiotics, Penicillin G was failure against all test organisms while Tetracycline and Amoxycillin were effective only against E. coli and Sarcina lutea respectively