Value of immunodiagnosis of pulmonary aspergillosis: about 327 serodiagnosis

ABSTRACT

Value of immunodiagnosis of pulmonaly aspergillosis [327 sera]. 327 sera from 214 patients the most of whom were tuberculous have been tested for antibodies to Aspergillus fumigatus, flavus, nigel; nidulans and terreus, by counterimmunoelectrophoresis in an agar gel coated support. Positive sera have been controled by immunoelectrophoresis. 10% of sera investigated were positive and 12% of patients had antibodies. Antibodies to Aspergillus fumigatus have been detected in 78,8% of pulmonary aspergillosis and in 58% of aspergilloma. Neither radiology, nor culture have been helpful for the diagnosis. The immunodiagnosis was negative one to 18 months after medical treatment