Study of gamma-interferon in schhistosomiasis mansoni, autoimmune diseases and schistosomal arthhropathy
Journal of the Egyptian Society of Parasitology. 1999; 29 (3): 721-734
in English
| IMEMR
| ID: emr-51181
ABSTRACT
IFN-gamma, aTh1 cytokine, was quantitatively estimated using EASIA in the sera of patients with different stages of Schistosomiasis mansoni autoimmune diseases and schistosomal arthropathy. Level of IFN-gamma was significantly elevated in all the test groups compared to the control group. The highest level of IFN-gamma observed was in RA and SLE with insignificant statistical difference between them. Cases with early S. mansoni infection showed significant higher level of IFN-gamma compared to hepatosplenic schistosomiasis with and without ascites. A significant statistical difference concerning IFN-gamma level was observed when comparing RA and SLE to different stages of S. mansoni infection and schistosomal arthropathy. This study concluded that IFN-gamma estimation in sera of patients having joint complaint could be a good marker for differentiation between autoimmune collagen induced arthritis and schistosomiasis induced arthropathy
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Arthritis
/
Arthritis, Rheumatoid
/
Autoimmune Diseases
/
Interferon-gamma
/
Lupus Erythematosus, Systemic
Limits:
Humans
Language:
English
Journal:
J. Egypt. Soc. Parasitol.
Year:
1999
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