Study of serum amylin in liver cirrhosis with diabetes mellitus

ABSTRACT

This study aimed to evaluate plasma amylin level in patients with chronic liver disease with and without diabetes. The study included 20 patients with liver cirrhosis and diabetes mellitus [12 males and eight females], ten patients with liver cirrhosis and normal glucose tolerance [eight males and two with a mean age of 49.5 +/- 12.9 years] and ten patients with NIDDM without liver disease [two males and eight females with a mean age of 56.1 +/- 7.4 years] in addition to ten healthy individuals as controls [six males and four females with a mean age of 39.4 +/- 4.1 years]. In all patients and controls, an oral glucose tolerance test was done and the levels of plasma C-peptide and amylin [using RIA kits] were measured