Bronchial response to methacholine inhalation challenge in families with and without asthma
Scientific Journal of Al-Azhar Medical Faculty [Girls] [The]. 1999; 20 (Supp. 1): 1455-1462
in English
| IMEMR
| ID: emr-52661
ABSTRACT
This study included 140 subjects; 20 asthmatic patients, 60 as first degree relative to asthmatics and 60 from non-asthmatic families. The results showed that all asthmatic patients were highly responders to methacholine inhalation challenge with a PD20 FEV1 less than 600 ug. The responders in asthmatic families were seven cases, but in non- asthmatics families, only three cases responded to methacholine inhalation challenge. This indicated that bronchial hyperresponse to methacholine is not due to environmental factor alone, but a combination of both environmental and genetic factors are responsible for bronchial hyperreactivity
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Respiratory Function Tests
/
Bronchi
/
Methacholine Chloride
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Sci. J. Al-Azhar Med. Fac. [Girls]
Year:
1999
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