Detection of some antipsychotics in hair and nail

ABSTRACT

Measurement of therapeutic drug concentration have most commonly been determined from body fluids that reflect drug use within few days prior to sampling, therefore cannot distinguish between acute or chronic drug use. In the current study, human hair and nail were used for analysis to detect antipsychotic drugs [haloperidol and chlorpromazine] in cases of prolonged exposure. The patients selected were using the drugs for four months to give chance for nail and hair containing during to appear. Twenty patients were chosen, ten for each drug. Their ages were between 26-59 of either sex. Hair and nail samples taken after four months were positive