Can we increase hepatic oxygen availability? the role of intentional hypercarbia
Middle East Journal of Anesthesiology. 2000; 15 (5): 503-514
in English
| IMEMR
| ID: emr-54695
ABSTRACT
Our hypothesis is that hypercarbia produces sympathetic stimulant effect and local vasodilatation. We studied the effect of intentional hypercarbia [IHC] on hepatic venous oxygen saturation. The hepatic vein [HV] was cannulated in 15 patients through either the right internal jugular vein or the femoral vein to measure HV oxygen saturation and calculate oxygen content. The inferior vena cava [IVC] was cannulated in 6 patients above and below drainage of the hepatic veins for oxygen saturation and content difference along the IVC. IHC was achieved in awake patients by breathing oxygen enriched air at a flow rate of 2L/ min for 10 min, and during anesthesia by increasing anesthetic dead space and reducing tidal volume. IHC increased HV blood oxygen saturation, decreased the arterio-hepatic vein oxygen content difference and decreased oxygen saturation difference and oxygen content difference along IVC
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Vena Cava, Inferior
/
Hepatic Veins
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Middle East J. Anesthesiol.
Year:
2000
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