Hypersensitivity to house dust mite and storage mite in relation to the clinical picture of scabies

ABSTRACT

In this study, 50 patients with the typical clinical picture of scabies were subjected to direct parasitological examination to detect sarcoptes scabiei and to estimate their skin reactivity to antigens of house dust mite [HDM], Dermatophagoides pteronyssinus [DP] and storage mite [SM] Tyrophagus putrescentia [TP]. Intradermal skin prick test [SPT] by the mentioned antigens showed highly significant positive results in patients when compared with the normal subjects. The rate of successful treatment to eradicate scabies was significantly higher among cases who had weak and negative skin reaction to DP and TP in comparison with that of cases with strongly positive SPT reaction to the same antigens