Effect of rocuronium compared with succinylcholine on intraocular pressure during rapid sequence induction of anaesthesia

ABSTRACT

In this work, the effect of rocuronium and succinylcholine on IOP during rapid sequence induction of anesthesia using propofol and fentanyl were studied in 40 ASA grade I adult patients of both sexes who required tracheal intubation as a part of the anesthetic technique for elective non-ophthalmic surgery. The patients were divided into two groups, each of 20 patients. Anesthesia was induced by fentanyl mug/kg and a sleep dose of propofol until loss of verbal response. It was found that IOP in the succinylcholine group was significantly greater than that in the rocuronium group. Intubating conditions were equally good in both groups. The results confirmed that with a rapid sequence induction of anesthesia using propofol and fentanyl, rocuronium did not cause an increase in IOP and provided excellent to good intubating conditions in a dose of 0.9 mg/kg at 60 s after administration