Granulomatose septique chronique chez une fillette revelee par une aspergilose pulmonaire invasive et une paraplegie flasque

ABSTRACT

The invasive Pulmonary Aspergillosis [lPA] is the principal cause of death in patients with chronic granulomatosis disease [CGD]. It can happen before age of one and can reveal the [CGD]. Usually, the transmission of GSD is linked to in 65% of cases. We report, the case of a girl aged 3 years issued from consanguine mariage referred to hospital for hemoptysia. We note that at 40 days she presents an suppurate adenitis. She is hypotrophic at 3DS without respiratory problem, she has a splenomegaly. The radiography chest note an alveolar and interstitiel opacity bilateral, apical right and basal left. There is a biological inflammatory syndrome. During the evolution, the child presents a paraplegia secondary to cornpression myelitis. A D5 laminectomy in urgency was done. The vertebral Biopsia, the serology and the culture isolate fumigatus aspergillus the GCD is evoqued confirmed by the NBT test who was negatif. In We have to look for GCD in front of pulmonary aspergillus The vertebra lesion is secondary to pulmonary lesion. Our observation is noticeable by the recessive autosomal transmission who was seen in 35% of cases, and by the neurologic complication rarely reported