Alkylation of indole with Baroylacrylic acids and some studies on the alkylated products

ABSTRACT

A large number of pyridazinones are reported to exhibit insecticidal and bactericidal activities. This prompted us to synthesise a new series of pyridazinones through the alkylation of indole with Beta-aroylacrylic acids followed by cyclization with hydiazines to the corresponding pyridazinone, the synthesis of various compounds prepared are outlined in Schemes 1-6