Prediction of clinical remission in systemic lupus erythematosus

ABSTRACT

The possible laboratory test[s] that could predict clinical remission was investigated in a group of 33 active systemic lupus erythematosus patients [SLE] in a prospective randomized study. The results showed a significant positive correlation between the duration of the treatment and SLE disease activity index [SLEDAI] score. Stepwise multiple linear regression analysis revealed that urine neopterin and C3 correlate with SLEDAI score during remission. Logistic regression analysis showed that patients had decline in the values of urine neopterin and urine neopterin/creatinine ratio was more likely to enter clinical remission than those with persistent higher values