Study of risk factors for carcinoma breast in adult female general population in Lahore

ABSTRACT

To evaluate some of the established risk factors for the breast cancer in adult female population. Design: It was a prospective study. Place and Duration This study was conducted in Oncology Department, Services Hospital, Lahore, from August, 1999 to August, 2000. Subject and One hundred breast cancer patients and 100 control subjects enrolled for interview and the percentage of positives was analyzed. Proforma containing demographic characteristics and established risk factors for breast cancer was established. All the female subjects, above 15 years of age, were subjected to the questions in this proforma. To keep uniformity medical officers were briefed for filling this proforma. The data gathered was analyzed statistically. Out of established risk factors, family history of breast cancer and use of oral contraceptive pills were proved significantly positive with a value of p<0.001, infertility and history of early menarche was positive with statistically significant difference of p<0.05. Menstrual disturbance, late menopause, history of pregnancy after 30 years of age and history of breast-feeding had no statistically significant difference [p>0.05]. This study showed that there is a family tendency for breast cancer and estrogenic hormones are playing some role. More possibility of breast cancer was found in infertile and those having early menarche