pathogenesis of Demodex folliculorum [hair follicular mites] in females with and without Rosacea

ABSTRACT

In rosacea patients [ages 11-50 years old] 44% were infested with D. folliculorum as compared to normal controls [23.0%]. The difference was significant. The mean +/- SD of mite density ranged between 13.2 +/- 0.9 to 18.2 +/- 1.2 as compared to normal controls with mite density ranged between 1.4 +/- 0.25 to 2.4 +/- 0.3. Demodex infestation in rosacea patients was 66.1% in squamous, 66.7% in erythemato-telangiectate and 83.3% in papulo pustular rosacea. The highly infested site was check [27.3%] with mean mite density of 25.3 +/- 1.3, followed by the area around the orbit [23.4%] with a density of 19.0 +/- 1.2, the area around the nose [19.5%] with mite density of 7.1 +/- 1.5, then chin [15.6%] with a density of 8.2 +/- 1.4 and lastly the area around the mouth [14.1%] with a mite density of 14.2 +/- 1.3. Undoubtedly, infestation with D. folliculorum particularly in large number causes rosacea