HCG test in Egyptian patients with cryptorchidism

ABSTRACT

Serum testosterone [T] concentration and urine 17 - Ketosteroid [17-KS] were determined under basal conditions and after stimulation by human chorionic gonado trophins [HCG] in thirty-six prepubertal males [10 normal children and 26 cryptorchid patients]. As a function of HCG stimulation, the increase in serum T level was evident in both groups, although the magnitude of rise was higher in control group than cryptorchid boys. No significant differences were obtained between unilateral and bilateral undesecended testis patients at basal level or after of the wide individual variations in testicular response in all subjects studied, yet the test is of value in assessing leydig cell function and in prognosis as regards virilization at puberty