Effects of formalin as a peripheral noxious stimulus on the nucleus reticularis paragigantocellularis neurons of ansethetized rats
Medical Journal of the Islamic Republic of Iran. 2001; 15 (2): 109-114
in English
| IMEMR
| ID: emr-57660
ABSTRACT
In the present study, the effects of formalin as a peripheral noxious stimulus on spontaneously active units of the nucleus reticularis paragigantocellularis [PGi], a narrow region of the ventral pontine reticular formation, was examined in urethane anesthetized rats. Spontaneous discharge of the PGi neurons was variable, ranging from I to 37 spikes per second. Formalin as a chemical irritant and prolonged noxious stimulus induced changes in the firing of spontaneously active PGi neurons. There were three neuronal subpopulations in the PGi that responded to formalin excited [19.35%], inhibited [45.16%] and unchanged [35.48%]. Thus we suggest that PGi neurons may be involved in the processing of information related to formalin as a chemical irritant
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Rats
/
Reticular Formation
/
Anesthesia
/
Neurons
Limits:
Animals
Language:
English
Journal:
Med. J. Islamic Rep. Iran
Year:
2001
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