Early versus late excision and grafting in the treatment of second and third degree burns

ABSTRACT

One hundred seventy eight patients with second or third degree burns who attended the emergency department in Suez Canal University Hospital in whom the total body burned surface area [TBSA] ranged between 10- 50% were included in our study. They were allocated randomly into two equal groups using simple randomization technique. [n= 89 patients]. Patients of the first group were treated by early excision of eschars and auto grafting [EEG], after a mean period of 5.39 +/- 1.47 days while patients of the second group were treated by repeated eschar excision, wound dressing and late grafting [LEG] after a mean period of 39.12 +/- 18.26 days [P<0.0001]. The mean graft take was 95.38% +/- 7.70 in the EEG group while it was 94.37% +/- 6.81 in the EEG group. The difference was statistically insignificant. Hypertrophic scars were common among patients of EEG group [41.57%] compared to [26.96%] in LEG group. It declined to 35% in EEG group compared to 30% in LEG group when burned surface area was equal or below 20% of [TBSA]. Late contracture was less common among patients of EEG group [6.74%] compared to [24.71%] in LEG group [P<0.001]. It declined to 0% in EEG group compared to 25% in LEG group when burned surface area was equal or below 20% of [TBSA]. The overall mortality was 5.06% [9 patients]. All mortalities had a burned surface area of 40-50%, it was due to septicaemia in 6 patients [3.37%], acute renal failure in 2 patients [1.12%] and DIC in one patient [0.56%]. Five of them [5.62%] were in EEG group and 4 [4.49%] were in the LEG group [NS]. The mean hospital stay was shorter in the EEG group [22.75 +/- 22.58 days] compared to [61.43 +/- 22.01 days] in the LEG group [p=0.0002]. We recommend the use of EEG in the management of second and third degree burn