Clinicopathological studies on fascioliasis among sheep in Giza province

ABSTRACT

The present study was carried out on 60 balady sheep of 3-5 years old belonged to several private farms located in Giza province. By clinical and laboratory diagnostic methods, 45 animals were proved to be naturally infested with Fasciola gigantica [infested group], the other 15 were healthy and served as the control group. Some biochemical and haematological parameters were evaluated. The results revealed significant hypoproteinaemia associated with significant hypoalbuminaemia and non significant hyperglobulinaemia were recorded in the infested group. Significant decrease in serum glucose and total cholesterol accompanied with significant increase in serum total bilirubin and both the direct and indirect bilirubin in naturally infested sheep. The enzymatic activities of the infested group showed significant elevation in serum AST, ALT and ALP with non significant alteration in serum level of LDH. The haemogram of the infested sheep showed significant deceased level of RBCs count, PCV and Hb content accompanied with leukocytosis