Laparoscopic ovarian electrocautery for clomiphene citrate resistant patients with polycystic ovary syndrome retrospective study

ABSTRACT

to evaluate the effect of ovarian electrocautery on ovarian response and pregnancy rate [PR] in clomiphene citrate [CC] resistant women with polycystic ovary syndrome [PCO]. Design retrospective study. Setting infertility clinic in a referral center. Patients and methods ninety seven patients with PCO who failed medical treatment with CC underwent laparoscopic ovarian elctrocautery. Hormonal profile, pregnancy rates and pattern of cycles before the electrocautery were compared for the same patient with those after the procedure improvement in the pattern of cycles in for resumption of regular cycles was noted with cumulative PR of 59.8%. There was a significant reduction in the luteinizing hormone [LH] level after ovarian electrocautery while there was no significant change in levels of follicular stimulating hormone [FSH], androstenedione [A], or testosterone [T] our results indicate that laparoscopic ovarian electrocautery is an effective tool to induce ovulation in CC-resistant PCO patients probably through reduction of basal LH levels