Clinicopathological and immunological study of brain tumours at L.G.H. Lahore

ABSTRACT

Thirty one patients with different types of brain tumors at LGH Lahore were studied .Age, sex, ethnic background and date of diagnosis were recorded. Children below the age of 15 years were 30%. Preopendrance was notable. Most common syndromes were headache, cranial nerve involvement, vomiting, papilloedema and behavioural changes. Gliomas constitute 38%, followed by neurinoma 22%, medulloblastoma and meninginoma, CSF glucose, total protein, CSF cytology, abumin, I[g]G, I[g]A and I[g]M were setermined. CSF glucose was not affected, while total protein, albumin, I[g]G, I[g]A and I[g]M were higher in brain tumour. I[g]G and I[g]A were significantly higher in malignant tumours than benign ones. Increased concentraton of immunoglobulins in CSF suggest humor immune response of brain against neoplasm