Hematological risk factors for cononary heart disease
Medical Principles and Practice. 2002; 11 (Supp. 2): 56-69
in English
| IMEMR
| ID: emr-60192
ABSTRACT
Coronary heart disease [CHD] is a leading cause of morbidity and mortality in the developed and developing countries. Several underlying genetic and environmental factors have been implicated in its etiology. Some of the hematological risk factors implicated in the development of coronary heart disease include antithrombin III deficiency, protein C and protein S deficiency, factor V Leiden mutation, prothrombin gene [20210A] mutation hyperhomocystinaemia, elevated factor VIII levels, plasminogen activator inhibitor type 1 and dysfibrinogenaemia. In general, these factors result in thrombosis, thus having a negative effect on the heart and blood vessels. This paper presents an overview of some of the hematological risk factors involved in the development of CHD
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Arteriosclerosis
/
Blood Coagulation Factors
/
Factor V
/
Fibrinogen
/
Prothrombin
/
Cardiovascular Diseases
/
Risk Factors
/
Plasminogen Activator Inhibitor 1
/
Coronary Disease
/
Homocysteine
Language:
English
Journal:
Med. Princ. Pract.
Year:
2002
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