Use of tranexamic acid in pediatric Kaposiform hemangio-endothelioma complicated with Kasabach-merritt syndrome
New Egyptian Journal of Medicine [The]. 2002; 27 (6): 360-367
in English
| IMEMR
| ID: emr-60309
ABSTRACT
Kasabach-Merritt syndrome is an infrequent combination of Kaposiform hemangio-endothelioma and severe thrombocytopenia, which may be life- threatening with an overall mortality rate of 20-30% and for which there are no definitive methods of treatment. A retrospective data collection of a single institute [KFSHRC]* reporting three cases of Kasabach-Merritt syndrome, showing a very good response to tranexamic acid with the reversal of the hematological disorder, decrease in steroid requirement and diminution of the size of the lesion in few months duration. The early use of tranexamic acid in the treatment of Kasabach-Merritt syndrome, especially the non-resectable vascular tumors, was recommended to be combined with interferon-alpha or steroid therapy for children
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Syndrome
/
Thrombocytopenia
/
Tranexamic Acid
/
Child
/
Retrospective Studies
/
Follow-Up Studies
/
Treatment Outcome
/
Hemangioendothelioma
Limits:
Female
/
Humans
Language:
English
Journal:
New Egypt. J. Med.
Year:
2002
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