Effect of experimental smoking demonstrated in articular cartilage of albinorats
New Egyptian Journal of Medicine [The]. 2002; 27 (Supp. 2): 23-27
in English
| IMEMR
| ID: emr-60323
ABSTRACT
Thirty-six adult albino rats 2-3 months old were used in this study, 30 of them were subjected to a daily heavy tobacco inhalation for three months in a dose equivalent to 1 mg nicotine/kg b. w./day and the remaining 6 rats were left as controls. Knee paraffin sections were prepared after sacrificing the rats, stained with H and E and Masson's trichrome. A morphometric analysis was done using an image analyzer with an optical magnification of X400 on routine H and E sections. It was concluded that the experimental heavy smoking in albino rats had a deleterious effect on the integrity of articular cartilage leading to a severe proliferation in addition to an increased water content of collagen matrix which is known to precede degeneration
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Rats
/
Smoking
/
Cartilage, Articular
/
Histology
Limits:
Animals
Language:
English
Journal:
New Egypt. J. Med.
Year:
2002
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