effect of a hypothalamic lesion on blood cholestrol in the lizard, uromastix hardwickii

ABSTRACT

The study evaluates TBC [Total Blood Cholesterol] during complete starvation following a hypothalamic lesion. For this purpose 240 lizards were divided into three groups. Animals of groups A and B were kept in captivity. Group A represented only starved animals. While group B represented starved lesioned Group. Group C consisted of 10 fresh animals purchased very day to represent a fed group. The cholesterol estimation of A, B and C groups was done from day 1 to day 7 Sachet's method. Results showed presence of hypocholestrolemia in group A animals during starvation. The decline being great from day 5 to 7. In response to the hypothalamic lesion in group B animals cholesterol increased on day 1, steeply declined on day 2 and then gradually increased till days 7