Scientific Journal of Al-Azhar Medical Faculty [Girls] [The]. 2002; 23 (1): 735-44
in English
| IMEMR
| ID: emr-60970
ABSTRACT
In a randomized study, the effect of whole blood transfusion versus packed RBCs transfusion on CD4+CD8+ ratio, the levels of soluble interleukin 2 receptor [sIL-2R] and interleukin IL-6 as well as on the development of the postoperative wound infection and intra-abdominal abscess, was assessed in 45 patients undergoing elective colorectal surgery. The patients were subdivided into three groups Group A included 13 patients who were randomly selected received whole blood transfusion when blood transfusion was indicated, group B included 13 patients who were randomly selected received packed RBCs when blood transfusion was indicated and group C included 19 patients who did not receive any blood transfusion. The samples were obtained prior operation and 3, 7 and 30 days postoperatively. The study demonstrated that transfusion with whole blood in elective colorectal surgery was followed by a significant depression in immunocompetence and this depression is attenuated by the use of packed RBCs transfusion
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Postoperative Complications
/
Surgical Wound Infection
/
CD4 Antigens
/
Randomized Controlled Trials as Topic
/
Immunosuppression Therapy
/
Interleukin-6
/
Interleukin-2
/
CD8 Antigens
/
Elective Surgical Procedures
/
Colorectal Surgery
Type of study:
Controlled clinical trial
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Sci. J. Al-Azhar Med. Fac. [Girls]
Year:
2002
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