Synthesis and evaluation of some new 2.4- [1H.3H] -quinazolinedione derivatives as potential analgesic and anti-inflammatory agents
Egyptian Journal of Pharmaceutical Sciences. 2003; 44 (1): 87-99
in English
| IMEMR
| ID: emr-61924
ABSTRACT
A series of 1-[3-trifluoromethylphenyl]-2, 4-[1H,3H]- quinazolinedione derivatives was synthesized as potential analgesic and anti- inflammatory agents. Structures were confirmed by elemental analysis and spectral data. Five compounds were tested for analgesic and anti- inflammatory activities. Two compounds II and VI exhibited significant analgesic and anti-inflammatory activities compared with flufenamic acid
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Chemistry, Pharmaceutical
/
Anti-Inflammatory Agents, Non-Steroidal
/
Drug Evaluation
Language:
English
Journal:
Egypt. J. Pharm. Sci.
Year:
2003
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