Analgesic, anti-inflammatory and antimicrobial activity of the leaves extract of Acalypha indica

ABSTRACT

The analgesic activity of the dried leaves' extract of Acalypha indica was studied after oral administration in mice using the acetic acid induced writhing method. The analgesic activity of the various extracts like petroleum ether, chloroform and methanol was studied. There was significant analgesic activity of the extracts of chloroform and methanol whereas petroleum ether's extract does not possess analgesic activity. The anti-inflammatory effect was studied by using histamine included paw oedema for different extracts. All the three extracts showed highly significant effect for this activity. Extracts tested against some gram negative and gram positive micro-organisms by two-fold serial dilution method were found to be devoid of anti-bacterial activity