Molluscicidal and in-vitro Schistosomicidal activities of the latex and some extracts of some plants belonging to Euphorbiacea

ABSTRACT

The molluscicidal activities of the natural and lyophilized latex extracts of Euphorbia royleana and E. Mouritanica as well as acetonitrile and chloroform extracts of Jatropha carcus were investigated against Biomphalaria alexandrina the intermediate hosts for S. Mansoni. The lyophilized latex extract of E. royleana showed the highest toxicity against the snails with LC90 value of 11 ppm. While, the natural latex extract of E. mouritanica showed the lowest toxicity against the snails with LC90 value of 60 ppm. The acetonitrile extract of Jatropha carcus gave a high toxicity against the snails with LC90 value of 6 ppm and the chloroform extract gave a low toxicity with LC90 value of 55 ppm. The in vitro schistosomicidal activities of lyophilized latex extract of E. Royleana and the acetonitrile extract of J. Carcus were studied against S. Mansoni adults showed that the lyophilized latex extract of E. Royleana gave 100% mortality after exposure to 30 ppm for 4 consecutive days and 66.7% mortality after exposure to 10 ppm for 5 consecutive days. The acetonitrile extract of J. carcus gave 91.7% mortality after exposure to 100 ppm for 4 consecutive days and 58.3% mortality after exposure to 50 ppm for 5 consecutive days