Effects of diazepam and promethazine on uterine contractions induced by prostaglandin E2 [PGE2]

Sibghatullah, Sangi; Kausar, Amir; Jamal, Ara; Saeed A., Mahar

Sibghatullah, Sangi; Kausar, Amir; Jamal, Ara; Saeed A., Mahar.

JSP-Journal of Surgery Pakistan International. 2003; 8 (1): 6-9

in English | IMEMR | ID: emr-63170

ABSTRACT

ABSTRACT

This study was conducted at Basic Medical Sciences Institute, Jinnah Post Graduate Medical Center, Karachi. It was done to observe the inhibitory effects of diazepam and promethazine, on uterine contractions induced by prostaglandin E2 [PGE.2]. The drug interaction, in vitro, proved that both diazepam and promethazine are tocolytic in vitro

Subject(s)

Animals, Laboratory; Diazepam/pharmacology; Promethazine/pharmacology; Prostaglandins E; Tocolysis; Labor, Induced; Pregnancy, Animal; Rats, Sprague-Dawley

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Index: IMEMR (Eastern Mediterranean) Main subject: Promethazine / Prostaglandins E / Pregnancy, Animal / Tocolysis / Rats, Sprague-Dawley / Diazepam / Labor, Induced Limits: Animals Language: English Journal: J. Surg. Pak. Int. Year: 2003

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