Correlation of CT scan and histopathology in brain tumours

ABSTRACT

The objective of this study was to determine the preoperative diagnostic accuracy of CT Scan in brain tumours and compare it with post operative histopathology results. This study was conducted at PNS Shifa Naval Hospital Karachi over a period of four years from December 1995 to December 1999. A total of 100 patients were included who underwent computed tomography [CT] scan for suspected brain tumours. Selection criteria included those single intracranial masses labeled as brain tumour on the basis of their CT features. Multiple lesions were excluded. The patients' age ranged from 13 85 years, mean age 43 years with male to female ratio 21 The common clinical presentations were headache, diplopia, seizures, personality changes, vertigo, vomiting and progressive neurological deficit. The results of our study revealed that out of hundred cases gliomas were 48, meningiomas 25, pituitary adenomas 12, craniopharyngiomas 6, pineal region tumours 4, acoustic neuromas 3 and choroid plexus papilloma 2. The diagnostic accuracy of CT scan was found to be 8396 on average, when correlated with histopathology