Serum testosterone and carotid atherosclerosis in men with type 2 diabetes: is there a link?
Mansoura Medical Journal. 2003; 34 (1-2): 231-253
in English
| IMEMR
| ID: emr-63419
ABSTRACT
This study included 50 male patients with type 2 diabetes aged 56.2 +/- 7.8 years, with a body mass index [BMI] of 28.3 +/- 2.6 kg/m 2, a duration of diabetes 10.6 +/- 6.4 years; in addition, 25 age- matched lean healthy subjects were taken as a control group. Body mass index [BMI], waist to hip ratio [WHR], plasma lipids, homeostasis model assessment of insulin resistance [HOMA-IR], plasminogen activator inhibitor-1 antigen [PAI-1 Ag] and plasma total testosterone [T] were assessed. Carotid intima-media thickness [IMT] and plaque score [PS] were evaluated by ultrasound. The study concluded that total serum testosterone is inversely associated with carotid atherosclerosis determined by ultrasonographically evaluated carotid IMT and PS in men with type 2 diabetes. Low serum testosterone is associated with an adverse cardiovascular risk profile in these patients
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Testosterone
/
Biomarkers
/
Carotid Artery Diseases
/
Body Mass Index
/
Plasminogen Activator Inhibitor 1
Type of study:
Controlled clinical trial
Limits:
Humans
/
Male
Language:
English
Journal:
Mansoura Med. J.
Year:
2003
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