Histiocyte-rich B-cell lymphoma: a case report of a rare variant of diffuse large B-cell lymphoma

ABSTRACT

The authors describe a case of histiocyte-rich B-cell lymphoma [HR-BCL], a variant of diffuse large B-cell lymphoma, in a 51-year-old man. The patient presented with large axillary lymphadenopathy. Histopathologic and immunohistochemical examination of lymph node biopsy revealed diffuse effacement of the lymph node architecture by reactive histiocytes and neoplastic CD20 positive B cells. Reactive histiocytes were negative for CD15 and CD30 immunostaining. The final diagnosis was histiocyte-rich B-cell lymphoma [HR-BCL] and the patient was referred to the oncology clinic for treatment