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Use of temozolomide in the management of high grade gliomas at relapse.
Medical Journal of Cairo University [The]. 2003; 71 (1): 147-57
in English | IMEMR | ID: emr-63604
ABSTRACT
This study was done at NEMROCK and other private as well as official governmental oncology centers, where 30 patients with residual or relapsed high grade gliomas received temozolomide at a dose of 200 mg/m2/day for five successive days to be recycled on day 21 for a total of six courses. Drug administration was quite safe with accepted toxicity profiles. The response parameters, including partial response, stationary disease and progressive neoplastic process, were documented in 33%, 45% and 22%, respectively
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Index: IMEMR (Eastern Mediterranean) Main subject: Recurrence / Astrocytoma / Tomography Scanners, X-Ray Computed / Treatment Outcome / Glioblastoma / Antineoplastic Agents, Alkylating / Disease Management Limits: Female / Humans / Male Language: English Journal: Med. J. Cairo Univ. Year: 2003

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Index: IMEMR (Eastern Mediterranean) Main subject: Recurrence / Astrocytoma / Tomography Scanners, X-Ray Computed / Treatment Outcome / Glioblastoma / Antineoplastic Agents, Alkylating / Disease Management Limits: Female / Humans / Male Language: English Journal: Med. J. Cairo Univ. Year: 2003