Gestational trophoblastic diseases [GTD]: Curable or fatal diseases? A single institution experience
Scientific Medical Journal. 2003; 15 (3): 5-21
in English
| IMEMR
| ID: emr-64900
ABSTRACT
The aim of this study was to define the treatment results and causes of failure including treatment toxicity in 48 patients with gestational trophoblastic diseases [GTD]. The clinical records of the patients were reviewed with regards to presentation, investigation, management and outcome. Thirty-nine patients received chemotherapy as they maintained high serum BHCG after suction and termination of molar pregnancy and other nine patients showed a progressive decline within one week and kept under follow up. Due to the relatively high toxicity of 4-day methotrexate outpatient schedule, it was recommended to shift to 1-day IV basis schedule. In case of extensive pulmonary metastasis, initial co-management with pulmonologist and ICU will be very beneficial to prevent ERD starting very carefully
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Radiotherapy
/
Uterine Neoplasms
/
Pregnancy
/
Choriocarcinoma
/
Methotrexate
/
Leucovorin
/
Retrospective Studies
/
Follow-Up Studies
/
Treatment Outcome
/
Chorionic Gonadotropin, beta Subunit, Human
Limits:
Female
/
Humans
Language:
English
Journal:
Sci. Med. J.
Year:
2003
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