Genetic role in recurrent acute otitis media
Zagazig University Medical Journal. 2003; (Special Issue-Nov.): 238-46
in English
| IMEMR
| ID: emr-65062
ABSTRACT
There is increasing interest that a strong genetic component is involved in the predisposition to recurrent acute otitis media [rAOM]. Study of human leucocyte antigens [HLA], as a genetic marker, by microcytotoxicity test and polymerase chain reaction [PCR] of 31 patients of rAOM was done to find out the relation between them for clarifying the pathogenesis of recurrence. The study showed HLA B21 antigen of class I and HLA DR2 antigen of class II were significantly increased p value. This supports the presence of an immunogenetic factor in pathogenesis of rAOM
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Index:
IMEMR (Eastern Mediterranean)
Main subject:
Recurrence
/
HLA-A Antigens
/
Polymerase Chain Reaction
/
Gene Frequency
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Zagazig Univ. Med. J.
Year:
2003
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